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Additionally, the effects of high doses or prolonged use of anabolic steroids on body composition or strength have not been scientifically documented. However, the use of anabolic steroid use by bodybuilders has been associated with obesity, fat deposits or excess abdominal fat (1-3). Consequently, steroids have been suggested as a potential underlying cause to the increase in obese individuals. The effect of anabolic steroids on the development and maintenance of obesity over a period of 15 years has not been established (4, 5). However, some investigators have found anabolic steroids reduce the development of metabolic syndrome (6). In addition, the effects of anabolic steroid use on insulin sensitivity, lipid profiles, and markers of inflammation in obese subjects may have direct effects on adipose tissue tissue and adipose tissue macrophages within the adipose tissue (5, 7). Indeed, it has been speculated that these hormones may exert indirect effects on adipose tissue macrophages, which in turn may have indirect effects on the development of obesity (8). Thus, the specific mechanisms by which steroids affect adipose tissue macrophage accumulation and adipose tissue inflammation are not well understood. However, the use of anabolic steroids increases the risk for certain diseases, such as hypertension and type 2 diabetes, and there are data to suggest that steroids increase the risk for obesity and insulin resistance (9, 10). These studies suggest that the use of anabolic steroids is associated with either an increased risk for or progression of obesity or insulin resistance. Thus, the use of anabolic steroids may induce the effects of anabolic steroids, which may exacerbate existing obesity. We tested the hypothesis that anabolic steroid exposure over a period of 15 years in overweight and obese subjects increases the risk for development of chronic liver inflammation and fatty liver in association with body composition changes. Materials and Methods Subjects Subjects consisted of 18 obese subjects (BMI: 25.9 ± 1.8 kg/m2; BMI-for-age 21.3 ± 0.6 kg/m2) from the University of Cincinnati and were selected from a previously published study (11). Twenty-one percent were female and 21% reported being active weightlifters (12). Subjects were aged 22 to 65 (mean ± SD). Subjects had a mean BMI (in kg/m2) of 31.1 ± 1.3 and a mean height of 184.2 ± 10.6 cm. The total body mass index (BMI) and the waist, hip, and arm circumferences were all >30 kg/m2. The subjects had regular use of oral and topical steroids ( Similar articles:

Buy anabolic steroids online with paypal, injectable steroids for sale in the usa
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